Publication

Computerised working memory‐based cognitive remediation therapy does not affect Reading the Mind in The Eyes test performance or neural activity during a Facial Emotion Recognition test in psychosis

Mothersill, David
Dillon, Rachael
Hargreaves, April
Castorina, Marco
Furey, Emilia
Fagan, Andrew J.
Meaney, James F.
Fitzmaurice, Brian
Hallahan, Brian
McDonald, Colm
... show 4 more
Citation
Mothersill, David, Dillon, Rachael, Hargreaves, April, Castorina, Marco, Furey, Emilia, Fagan, Andrew J., Meaney, James F., Fitzmaurice, Brian, Hallahan, Brian, McDonald, Colm, Wykes, Til, Corvin, Aiden, Robertson, Ian H., Donohoe, Gary. (2018). Computerised working memory-based cognitive remediation therapy does not affect Reading the Mind in The Eyes test performance or neural activity during a Facial Emotion Recognition test in psychosis. European Journal of Neuroscience, 48(1), 1691-1705. doi: doi:10.1111/ejn.13976
Abstract
Working memory-based cognitive remediation therapy (CT) for psychosis has recently been associated with broad improvements in performance on untrained tasks measuring working memory, episodic memory and IQ, and changes in associated brain regions. However, it is unclear whether these improvements transfer to the domain of social cognition and neural activity related to performance on social cognitive tasks. We examined performance on the Reading the Mind in the Eyes test (Eyes test) in a large sample of participants with psychosis who underwent working memory-based CT (N=43) compared to a control group of participants with psychosis (N=35). In a subset of this sample, we used functional magnetic resonance imaging (fMRI) to examine changes in neural activity during a facial emotion recognition task in participants who underwent CT (N=15) compared to a control group (N=15). No significant effects of CT were observed on Eyes test performance or on neural activity during facial emotion recognition, either at p
Publisher
Wiley
Publisher DOI
10.1111/ejn.13976
Rights
Attribution-NonCommercial-NoDerivs 3.0 Ireland