Publication

Dna repair: the importance of phosphorylating histone h2ax

Lowndes, Noel F.
Toh, Geraldine W.-L.
Citation
Lowndes, Noel F. Toh, Geraldine W.-L. (2005). Dna repair: the importance of phosphorylating histone h2ax. Current Biology 15 (3), R99-R102
Abstract
How phosphorylated histone H2AX, known as gamma-H2AX, functions in the cellular response to DNA double-strand breaks is the subject of intensive investigation. Recent research in yeast and mammalian cells shows that gamma-H2AX facilitates post-replicational DNA repair by recruiting cohesin, a protein complex that holds sister chromatids together.
Funder
Publisher
Elsevier BV
Publisher DOI
10.1016/j.cub.2005.01.029
Rights
Attribution-NonCommercial-NoDerivs 3.0 Ireland