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Protein – Calixarene frameworks via supramolecular synthons: A modular approach

Mockler, Niamh
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Identifiers
https://hdl.handle.net/10379/18663
 https://doi.org/10.13025/29457
Publication Date
2025-03-07
Keywords
Protein, Calixarene, supramolecular synthons, Biological and Chemical Sciences
Type
doctoral thesis
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Abstract
Anionic, water-soluble calixarenes act as protein receptors and mediators of assembly, towards protein crystal engineering. Reproducible structural units, known as supramolecular synthons, are identified across protein – calixarene crystal structures and applied to direct new frameworks. Controlled calixarene binding is applicable in disordered protein capture and molecular tectonics.
Funder
Irish Research Council
Publisher
University of Galway
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CC BY-NC-ND
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University of Galway Theses (PhD Theses)