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Genotypic characterisation and cluster analysis of campylobacter jejuni isolates from domestic pets, human clinical cases and retail food

Acke, Els
; 
Carroll, Cyril
; 
O'Leary, Aoife
; 
McGill, Kevina
; 
Kelly, Lorraine
; 
Lawlor, Amanda
; 
Madden, Robert H
; 
Moran, Lynn
; 
Scates, Pam
; 
McNamara, Eleanor
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Repository DOI
Publication Date
2011-01-01
Keywords
molecular characterization, young-children, risk-factors, dogs, ireland, cats, spp., transmission, prevalence, reservoirs
Type
Article
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Citation
Acke, Els; Carroll, Cyril; O'Leary, Aoife; McGill, Kevina; Kelly, Lorraine; Lawlor, Amanda; Madden, Robert H; Moran, Lynn; Scates, Pam; McNamara, Eleanor; Moore, John E; Jones, Boyd R; Fanning, Seamus; Whyte, Paul (2011). Genotypic characterisation and cluster analysis of campylobacter jejuni isolates from domestic pets, human clinical cases and retail food. Irish Veterinary Journal 64 ,
Abstract
The genetic similarity of Campylobacter jejuni isolates from pets, compared to human clinical cases and retail food isolates collected in Ireland over 2001-2006 was investigated by cluster analysis of pulsed-field gel electrophoresis (PFGE) fingerprinting profiles. Comparison of the PFGE profiles of 60 pet isolates and 109 human isolates revealed that seven (4.1%) profiles were grouped in clusters including at least one human and one pet C. jejuni isolate. In total six (1.6%) of 60 pet and 310 food profiles were in clusters with at least one food and one pet C. jejuni isolate. The detection of only a small number of genetically indistinguishable isolates by PFGE profile cluster analysis from pets and from humans with enteritis in this study suggests that pets are unlikely to be an important reservoir for human campylobacteriosis in Ireland. However, genetically indistinguishable isolates were detected and C. jejuni from pets may circulate and may contribute to clinical infections in humans. In addition, contaminated food fed to pets may be a potential source of Campylobacter infection in pets, which may subsequently pose a risk to humans.
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Publisher
Springer Nature
Publisher DOI
10.1186/2046-0481-64-6
Rights
Attribution-NonCommercial-NoDerivs 3.0 Ireland
cbn
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Externally hosted open access publications with University of Galway authors (2)