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Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: very strong correlation to pleurotin and thioredoxin reductase inhibition

Sweeney, Martin
; 
Coyle, Robert
; 
Kavanagh, Paul
; 
Berezin, Andrey A.
; 
Lo Re, Daniele
; 
Zissimou, Georgia A.
; 
Koutentis, Panayiotis A.
; 
Carty, Michael P.
; 
Aldabbagh, Fawaz
Repository DOI
Publication Date
2016-08-01
Keywords
anti-tumor, bioreduction, heterocyclic compound, nci-dtp compare program, toxicity, growth, assay, lead
Type
Article
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Citation
Sweeney, Martin; Coyle, Robert; Kavanagh, Paul; Berezin, Andrey A. Lo Re, Daniele; Zissimou, Georgia A.; Koutentis, Panayiotis A.; Carty, Michael P.; Aldabbagh, Fawaz (2016). Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: very strong correlation to pleurotin and thioredoxin reductase inhibition. Bioorganic & Medicinal Chemistry 24 (16), 3565-3570
Abstract
Funder
Publisher
Elsevier BV
Publisher DOI
10.1016/j.bmc.2016.05.066
Rights
Attribution-NonCommercial-NoDerivs 3.0 Ireland
cbn
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Externally hosted open access publications with University of Galway authors (2)