Inhomogeneous deformation of brain tissue during tension tests

Destrade, Michel
Gilchrist, Michael
Rashid, Badar; Destrade, Michel; Gilchrist, Michael (2012) 'Inhomogeneous deformation of brain tissue during tension tests'. Computational Materials Science, 64 :295-300.
Mechanical characterization of brain tissue has been investigated extensively by various research groups over the past 50 years. These properties are particularly important for modeling Traumatic Brain Injury (TBI). In this research, we present the design and calibration of a High Rate Tension Device (HRTD) capable of performing tests up to a maximum strain rate of 90/s. We use experimental and numerical methods to investigate the effects of inhomogeneous deformation of porcine brain tissue during tension at different specimen thicknesses (4.0 14.0 mm), by performing tension tests at a strain rate of 30/s. One-term Ogden material parameters (μ = 4395.0 Pa, α = −2.8) were derived by performing an inverse finite element analysis to model all experimental data. A similar procedure was adopted to determine Young s modulus (E = 11200 Pa) of the linear elastic regime. Based on this analysis, brain specimens of aspect ratio (diameter/thickness) S /1.0 are required to minimise the effects of inhomogeneous deformation during tension tests.
Publisher DOI
Attribution-NonCommercial-NoDerivs 3.0 Ireland