Publication

Endoplasmic reticulum stress: at the crossroads of inflammation and metabolism in hepatocellular carcinoma development

Maurel, Marion
Samali, Afshin
Chevet, Eric
Repository DOI
Publication Date
2014-09-01
Type
Article
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Citation
Maurel, Marion; Samali, Afshin; Chevet, Eric (2014). Endoplasmic reticulum stress: at the crossroads of inflammation and metabolism in hepatocellular carcinoma development. Cancer Cell 26 (3), 301-303
Abstract
Steatohepatitis is a cause of hepatocellular carcinoma development; however, the underlying mechanisms are poorly defined. In this issue of Cancer Cell, Nakagawa and colleagues demonstrate that activation of endoplasmic reticulum stress signaling is instrumental in the development of steatohepatitis and synergizes with proinflammatory pathways to promote hepatocarcinogenesis.
Funder
Publisher
Elsevier BV
Publisher DOI
10.1016/j.ccr.2014.08.007
Rights
Attribution-NonCommercial-NoDerivs 3.0 Ireland