Publication

Endoplasmic reticulum stress: at the crossroads of inflammation and metabolism in hepatocellular carcinoma development

Maurel, Marion
; 
Samali, Afshin
; 
Chevet, Eric
Identifiers
http://hdl.handle.net/10379/12687
 https://doi.org/10.13025/26303
Publication Date
2014-09-01
Keywords
disease, activation, pathway, genes
Type
Article
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Citation
Maurel, Marion; Samali, Afshin; Chevet, Eric (2014). Endoplasmic reticulum stress: at the crossroads of inflammation and metabolism in hepatocellular carcinoma development. Cancer Cell 26 (3), 301-303
Abstract
Steatohepatitis is a cause of hepatocellular carcinoma development; however, the underlying mechanisms are poorly defined. In this issue of Cancer Cell, Nakagawa and colleagues demonstrate that activation of endoplasmic reticulum stress signaling is instrumental in the development of steatohepatitis and synergizes with proinflammatory pathways to promote hepatocarcinogenesis.
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Publisher
Elsevier BV
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Attribution-NonCommercial-NoDerivs 3.0 Ireland
cbn
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Externally hosted open access publications with University of Galway authors (2)