Adaptive living skills, sleep problems, and mental health problems in adults with 22q11.21 deletion syndrome
Leader, Geraldine Curtin, Andrea Shprintzen, Robert J. Whelan, Sally Coyne, Rory Mannion, Arlene
Leader, Geraldine
Curtin, Andrea
Shprintzen, Robert J.
Whelan, Sally
Coyne, Rory
Mannion, Arlene
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Publication Date
2023-03-23
Type
Article
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Leader, Geraldine, Curtin, Andrea, Shprintzen, Robert J., Whelan, Sally, Coyne, Rory, & Mannion, Arlene. (2023). Adaptive living skills, sleep problems, and mental health disorders in adults with 22q11.21 deletion syndrome. Research in Developmental Disabilities, 136, 104491. doi: https://doi.org/10.1016/j.ridd.2023.104491
Abstract
Background 22q11.21 deletion syndrome (22q11DS) is a neurodevelopmental syndrome caused by a microdeletion of genes at the 22q11.21 locus. It has a prevalence of 1:2000. This study investigated the prevalence of adaptive living skills, sleep problems, and mental health disorders in adults with 22q11DS and examined the relationship between these factors. Methods Parents with an adult son or daughter with 22q11DS completed the following: A bespoke Demographic Information Questionnaire, Sleep Questionnaire (SQ-SP), Psychopathology in Autism Checklist (PAC), and Activities of Daily Living (ADL) scale. Descriptive statistics, correlations, and one-way between groups analysis of variance (ANOVA) were conducted. Results Mental health difficulties, sleep problems, and low levels of adaptive living skills are prevalent in adults with 22q11DS. Strong positive correlations were identified between sleep problems, depression, and anxiety subscale scores and moderate negative correlations between depression, psychosis, and activities of daily living skills. Conclusion Adults with 22q11DS need screening and treatment for mental health and sleep problems.
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Publisher
Elsevier
Publisher DOI
10.1016/j.ridd.2023.104491
Rights
Attribution 4.0 International (CC BY 4.0)