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LcrG is required for efficient translocation of Yersinia Yop effector proteins into eukaryotic cells

Boyd, Aoife
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Identifiers
http://hdl.handle.net/10379/3885
 https://doi.org/10.13025/15525
Publication Date
1998-06
Keywords
Yersinia, Yop, lcrG
Type
Article
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Citation
Sarker MR, M-P Sory, A Boyd, M Iriarte and GR Cornelis. (1998) 'LcrG is required for efficient translocation of Yersinia Yop effector proteins into eukaryotic cells'. Infection and Immunity, 66 :2976-2979.
Abstract
Extracellular Yersinia disables the immune system of its host by injecting effector Yop proteins into host cells. We show that a Yersinia enterocolitica nonpolar lcrG mutant is severely impaired in the translocation of YopE, YopH, YopM, YpkA/YopO, and YopP into eukaryotic cells. LcrG is thus required for efficient internalization of all the known Yop effectors.
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Publisher
American Society for Microbiology
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Attribution-NonCommercial-NoDerivs 3.0 Ireland
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Microbiology (Scholarly Articles)