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First responders: understanding monocyte-lineage traffic in the acutely injured kidney

Swaminathan, Sundararaman
; 
Griffin, Matthew D.
Identifiers
http://hdl.handle.net/10379/14080
 https://doi.org/10.13025/26588
Publication Date
2008-12-01
Keywords
ischemia-reperfusion injury, dendritic cells
Type
Article
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Citation
Swaminathan, Sundararaman; Griffin, Matthew D. (2008). First responders: understanding monocyte-lineage traffic in the acutely injured kidney. Kidney International 74 (12), 1509-1511
Abstract
Interstitial monocytic infiltration of the kidney occurs within hours of acute kidney injury and is an important determinant of functional decline and fibrosis. Li et al. used several surface markers to distinguish between dendritic cells and inflammatory monocytes following acute kidney injury and to identify two chemokine receptors that regulate monocyte traffic. This Commentary examines the degree to which monocyte-lineage diversity, trafficking, and contribution to renal injury have been teased out to date.
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Publisher
Elsevier BV
Publisher DOI
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Attribution-NonCommercial-NoDerivs 3.0 Ireland
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Externally hosted open access publications with University of Galway authors (2)