Transcatheter heart valve failure: a systematic review
Mylotte, D. Andalib, A. Theriault-Lauzier, P. Dorfmeister, M. Girgis, M. Alharbi, W. Chetrit, M. Galatas, C. Mamane, S. Sebag, I.
Mylotte, D.
Andalib, A.
Theriault-Lauzier, P.
Dorfmeister, M.
Girgis, M.
Alharbi, W.
Chetrit, M.
Galatas, C.
Mamane, S.
Sebag, I.
Identifiers
http://hdl.handle.net/10379/13063
https://doi.org/10.13025/27145
https://doi.org/10.13025/27145
Repository DOI
Publication Date
2014-09-28
Keywords
aortic stenosis, transcatheter aortic valve implantation, transcatheter heart valve failure, prosthetic valve endocarditis, heart valve failure, transapical aortic-valve, balloon-expandable valve, edwards sapien valve, cardiopulmonary-resuscitation, infective endocarditis, corevalve prosthesis, bioprosthetic valve, clinical-outcomes, structural valve, core valve
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Article
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Citation
Mylotte, D. Andalib, A.; Theriault-Lauzier, P.; Dorfmeister, M.; Girgis, M.; Alharbi, W.; Chetrit, M.; Galatas, C.; Mamane, S.; Sebag, I.; Buithieu, J.; Bilodeau, L.; de Varennes, B.; Lachapelle, K.; Lange, R.; Martucci, G.; Virmani, R.; Piazza, N. (2014). Transcatheter heart valve failure: a systematic review. European Heart Journal 36 (21), 1306-U129
Abstract
Aims A comprehensive description of transcatheter heart valve (THV) failure has not been performed. We undertook a systematic review to investigate the aetiology, diagnosis, management, and outcomes of THV failure. Methods and results The systematic review was performed in accordance with the PRISMA guidelines using EMBASE, MEDLINE, and Scopus. Between December 2002 and March 2014, 70 publications reported 87 individual cases of transcatheter aortic valve implantation (TAVI) failure. Similar to surgical bioprosthetic heart valve failure, we observed cases of prosthetic valve endocarditis (PVE) (n = 34), structural valve failure (n = 13), and THV thrombosis (n = 15). The microbiological profile of THV PVE was similar to surgical PVE, though one-quarter had satellite mitral valve endocarditis, and surgical intervention was required in 40% (75% survival). Structural valve failure occurred most frequently due to leaflet calcification and was predominantly treated by redo-THV (60%). Transcatheter heart valve thrombosis occurred at a mean 9 +/- 7 months post-implantation and was successfully treated by prolonged anticoagulation in three-quarters of cases. Two novel causes of THV failure were identified: late THV embolization (n = 18); and THV compression (n = 7) following cardiopulmonary resuscitation (CPR). These failure modes have not been reported in the surgical literature. Potential risk factors for late THV embolization include low prosthesis implantation, THV undersizing/underexpansion, bicuspid, and non-calcified anatomy. Transcatheter heart valve embolization mandated surgery in 80% of patients. Transcatheter heart valve compression was noted at post-mortem in most cases. Conclusion Transcatheter heart valves are susceptible to failure modes typical to those of surgical bioprostheses and unique to their specific design. Transcatheter heart valve compression and late embolization represent complications previously unreported in the surgical literature.
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Publisher
Oxford University Press (OUP)
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Attribution-NonCommercial-NoDerivs 3.0 Ireland