Publication

Role of micro-rnas in breast cancer surgery

McAnena, P.
Lowery, A.
Kerin, M. J.
Citation
McAnena, P. Lowery, A.; Kerin, M. J. (2018). Role of micro-rnas in breast cancer surgery. British Journal of Surgery 105 (2), E19-E30
Abstract
Background: The management of breast cancer has changed dramatically in the molecular era. Micro-RNAs can contribute to multiple facets of cancer surgery. Methods: This narrative review, based on years of research on the role of micro-RNAs, focused on the potential of these small, robust RNAs to influence all aspects of breast cancer surgery. Results: Micro-RNAs have a potential role as biomarkers in the diagnosis, prognosis and evaluation of response to therapy in breast cancer. They may also contribute to future therapeutic strategies. Conclusion: The molecular era has changed understanding of cancer. Micro-RNAs have the potential for use in personalized cancer strategies.
Funder
Publisher
Wiley-Blackwell
Publisher DOI
10.1002/bjs.10790
Rights
Attribution-NonCommercial-NoDerivs 3.0 Ireland