Publication

Adaptive optics technology for high-resolution retinal imaging

Lombardo, Marco
; 
Serrao, Sebastiano
; 
Devaney, Nicholas
; 
Parravano, Mariacristina
; 
Lombardo, Giuseppe
Identifiers
http://hdl.handle.net/10379/12492
https://doi.org/10.13025/27824
Repository DOI
10.3390/s130100334
Publication Date
2012-12-27
Keywords
adaptive optical systems, optical sensors, biomedical imaging techniques, eye, wave-front sensor, scanning laser ophthalmoscope, higher-order aberrations, nerve-fiber layer, photoreceptor packing density, human cone photoreceptors, genome-wide association, of-intensity equation, macular degeneration, coherence tomography
Type
Article
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Citation
Lombardo, Marco; Serrao, Sebastiano; Devaney, Nicholas; Parravano, Mariacristina; Lombardo, Giuseppe (2012). Adaptive optics technology for high-resolution retinal imaging. Sensors 13 (1), 334-366
Abstract
Adaptive optics (AO) is a technology used to improve the performance of optical systems by reducing the effects of optical aberrations. The direct visualization of the photoreceptor cells, capillaries and nerve fiber bundles represents the major benefit of adding AO to retinal imaging. Adaptive optics is opening a new frontier for clinical research in ophthalmology, providing new information on the early pathological changes of the retinal microstructures in various retinal diseases. We have reviewed AO technology for retinal imaging, providing information on the core components of an AO retinal camera. The most commonly used wavefront sensing and correcting elements are discussed. Furthermore, we discuss current applications of AO imaging to a population of healthy adults and to the most frequent causes of blindness, including diabetic retinopathy, age-related macular degeneration and glaucoma. We conclude our work with a discussion on future clinical prospects for AO retinal imaging.
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Publisher
MDPI AG
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Attribution-NonCommercial-NoDerivs 3.0 Ireland
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Externally hosted open access publications with University of Galway authors (2)