Disturbing effect of intra-tissue temperature sensors in pre-clinical experimental studies of radiofrequency cardiac ablation: A computer-based modeling study

Cuenca-Dacal, Luis
Berjano, Enrique
González-Suárez, Ana
Pérez, Juan J.
Cuenca-Dacal, Luis, Berjano, Enrique, González-Suárez, Ana, & Pérez, Juan J. (2023). Disturbing Effect of Intra-Tissue Temperature Sensors in Pre-Clinical Experimental Studies of Radiofrequency Cardiac Ablation: A Computer-Based Modeling Study. Processes, 11(4), 1168.
Background: Preclinical studies on radiofrequency (RF) cardiac ablation (RFCA) use very small temperature sensors in specific positions in the tissue subjected to RF heating. Despite the sensors¿ small size, the proximity to the ablation electrode and the extremely high thermal gradient around the electrode means that the presence of the temperature sensors could distort the temperatures recorded. Our objective was to assess the thermal impact of intra-tissue temperature sensors during RFCA. Methods: 3D RFCA models were built including different temperature sensors based on fiber optics and T-type thermocouples. Constant power ablation was simulated for 10 s. Results: The results showed that the disturbance caused by the presence of the T-type thermocouples was considerably greater (one order of magnitude) than that caused by the optical fibers. The closer the sensor was to the ablation electrode, the greater the greater the disturbance was and the more it increased with time in sensors more than 3 mm deep. The fiber optic measurements always slightly underestimated (
Publisher DOI
Attribution 4.0 International (CC BY 4.0)