Microcavity array supported lipid bilayer models of ganglioside – influenza hemagglutinin1 binding
Berselli, Guilherme B. Sarangi, Nirod Kumar Gimenez, Aurélien V. Murphy, Paul V. Keyes, Tia E.
Berselli, Guilherme B.
Sarangi, Nirod Kumar
Gimenez, Aurélien V.
Murphy, Paul V.
Keyes, Tia E.
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http://hdl.handle.net/10379/16442
https://doi.org/10.13025/15041
https://doi.org/10.13025/15041
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Publication Date
2020-08-07
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Article
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Berselli, Guilherme B., Sarangi, Nirod Kumar, Gimenez, Aurélien V., Murphy, Paul V., & Keyes, Tia E. (2020). Microcavity array supported lipid bilayer models of ganglioside – influenza hemagglutinin1 binding. Chemical Communications, 56(76), 11251-11254. doi:10.1039/D0CC04276E
Abstract
The binding of influenza receptor (HA(1)) to membranes containing different glycosphingolipid receptors was investigated at Microcavity Supported Lipid Bilayers (MSLBs). We observed that HA(1)preferentially binds to GD1a but the diffusion coefficient of the associated complex at lipid bilayer is approximately double that of the complexes formed by HA(1)GM1 or GM3.
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Royal Society of Chemistry
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Attribution-NonCommercial-NoDerivs 3.0 Ireland