Publication

Analysis of a poly(ε-decalactone)/silver nanowire composite as an electrically conducting neural interface biomaterial

Krukiewicz, Katarzyna
Fernandez, Jorge
Skorupa, Małgorzata
Więcławska, Daria
Poudel, Anup
Sarasua, Jose-Ramon
Quinlan, Leo R.
Biggs, Manus J. P.
Citation
Krukiewicz, Katarzyna, Fernandez, Jorge, Skorupa, Małgorzata, Więcławska, Daria, Poudel, Anup, Sarasua, Jose-Ramon, Quinlan, Leo R., Biggs, Manus J. P. (2019). Analysis of a poly(ε-decalactone)/silver nanowire composite as an electrically conducting neural interface biomaterial. BMC Biomedical Engineering, 1(1), 9. doi: 10.1186/s42490-019-0010-3
Abstract
Advancement in polymer technologies, facilitated predominantly through chemical engineering approaches or through the identification and utilization of novel renewable resources, has been a steady focus of biomaterials research for the past 50 years. Aliphatic polyesters have been exploited in numerous biomedical applications including the formulation of soft-tissue sutures, bone fixation devices, cardiovascular stents etc. Biomimetic soft polymer formulations are of interest in the design of biological interfaces and specifically, in the development of implantable neuroelectrode systems intended to interface with neural tissues. Critically, soft polymer formulations have been shown to address the challenges associated with the disregulation of mechanotransductive processes and micro-motion induced inflammation at the electrode/tissue interface. In this study, a polyester-based poly(ε-decalactone)/silver nanowire (EDL:Ag) composite was investigated as a novel electrically active biomaterial with neural applications.
Publisher
BMC (part of Springer Nature)
Publisher DOI
10.1186/s42490-019-0010-3
Rights
Attribution-NonCommercial-NoDerivs 3.0 Ireland