Design and characterization of a three-layer collagen-based scaffold to modulate BMSC behaviour for enthesis regeneration
Pugliese, Eugenia Zeugolis, Dimitrios I.
Pugliese, Eugenia
Zeugolis, Dimitrios I.
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Identifiers
http://hdl.handle.net/10379/15974
https://doi.org/10.13025/20871
https://doi.org/10.13025/20871
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Publication Date
2019-04-08
Type
Conference Paper
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Citation
Pugliese, Eugenia, & Zeugolis, Dimitrios I. (2019). Design and characterization of a three-layer collagen-based scaffold to modulate BMSC behaviour for enthesis regeneration. Paper presented at the British Society for Matrix Biology (BSMB) Spring Meeting: Stroma, Niche, Repair, Liverpool, United Kingdom, 08 April.
Abstract
The enthesis is a specialised tissue interface between tendon and bone, essential for adequate force transmission. Following injuries and surgical repair, the enthesis is often not re-established and traditionally used tissue substitutes have lacked to reproduce the complexity of the native tissue. We hypothesised that a collagen-based three-layer scaffold that mimic the composition of the enthesis, in combination with bioactive molecules, will enhance the functional regeneration of the tissue.
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Publisher
Wiley
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Attribution-NonCommercial-NoDerivs 3.0 Ireland