Long-term costs of introducing hpv-dna post-treatment surveillance to national cervical cancer screening in ireland
Agapova, Maria ; Duignan, Andrea ; Smith, Alan ; O’Neill, Ciaran ; Basu, Anirban
Agapova, Maria
Duignan, Andrea
Smith, Alan
O’Neill, Ciaran
Basu, Anirban
Identifiers
http://hdl.handle.net/10379/10127
https://doi.org/10.13025/28603
https://doi.org/10.13025/28603
Repository DOI
Publication Date
2015-09-17
Type
Article
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Citation
Agapova, Maria; Duignan, Andrea; Smith, Alan; O’Neill, Ciaran; Basu, Anirban (2015). Long-term costs of introducing hpv-dna post-treatment surveillance to national cervical cancer screening in ireland. Expert Review of Pharmacoeconomics & Outcomes Research 15 (6), 999-1005
Abstract
Introduction: Co-testing (cytology plus human papillomavirus DNA testing) as part of cervical cancer surveillance in Ireland increases one-time testing costs. Of interest to policy makers was the long-term impact of these costs accompanied by decreases in intensity of recalls for women with no detected abnormalities. Methods: A cost analysis of cytology-only and co-testing strategy was implemented using decision analytic modeling, aggregating testing utilization and costs for each of the two strategies over 12 years. Results: Aggregated incremental costs of the co-testing strategy were positive for the first 3 years but became negative thereafter, generating a cost savings of roughly Euro20 million in favor of the cytology-only strategy over a 12-year period. Results were robust over a range of sensitivity analyses with respect to discount and attrition rates. Discussion: This analysis provided valuable information to policy makers contributing to the introduction of co-testing for post-treatment surveillance (PTS) in Ireland.
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Publisher
Informa UK Limited
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Rights
Attribution-NonCommercial-NoDerivs 3.0 Ireland