Publication

Characterizing protein modifications by reactive metabolites using magnetic bead bioreactors and lc-ms/ms

Li, Dandan
Fu, You-Jun
Rusling, James F.
Citation
Li, Dandan; Fu, You-Jun; Rusling, James F. (2015). Characterizing protein modifications by reactive metabolites using magnetic bead bioreactors and lc-ms/ms. Chem. Commun. 51 (22), 4701-4703
Abstract
We report here label-free metabolite-protein adduct detection and identification employing magnetic beads coated with metabolic enzymes as bioreactors to generate metabolites and possible metabolite-protein adducts for analysis by liquid chromatographytandem mass spectrometry.
Funder
Publisher
Royal Society of Chemistry (RSC)
Publisher DOI
10.1039/c5cc00420a
Rights
Attribution-NonCommercial-NoDerivs 3.0 Ireland